Artemisinin based combination therapies (ACTs) have become the front line drugs for treatment of malaria after the phasing out of chloroquine and the other monotherapeutics due to resistance mounted by the Plasmodium parasites.
But how much do we know about the discovery of the drug(s) that have changed the face of the malaria world, salvaging many lives.
With resistance to artemisinin mounting in South East Asia, and showing trace signatures in Africa, it is obvious that novel strategies are required to keep the malaria disease in check until subsequent elimination. This would also be in honor of the 2015 Nobel Prize Laureate in Physiology and Medicine, Youyou Tu.

